Product Datasheet  
MCAM(CD146) Antibody  
Catalog Number: 48005  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P43121
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Ms,Rt
  • appl_detail：  
  • WB: 1:500



  • other_names：  
  • A32 antigen antibody
    CD 146 antibody
    CD146 antibody
    CD146 antigen antibody
    Cell surface glycoprotein MUC18 antibody
    Cell surface glycoprotein P1H12 antibody
    Gicerin antibody
    Mcam antibody
    Melanoma ad
  • Purification：  
  • Immunogen affinity purified
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • CD146 is a cell surface glycoprotein, originally identified as a melanoma antigen, whose expression is associated with tumor progression and the development of metastatic potential. Overexpression of CD146 in breast carcinoma cells results in a more cohesive cell growth and in the formation of smaller tumors in nude mice. During implantation and placentation, CD146 is expressed by the intermediate trophoblast in the placental site and binds to its putative receptor in uterine smooth muscle cells thus limiting trophoblastic invasion in the myometrium.



 
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