Product Datasheet
SCA-1 Antibody
Catalog Number: 47996
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P05533
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- other_names:
- Ly-6A.2/Ly-6E. antibody Ly-6A.2/Ly-6E.1 antibody Ly6a antibody LY6A_MOUSE antibody Ly6al antibody Lymphocyte antigen 6A-2/6E-1 antibody Lymphocyte antigen Ly 6A.2/Ly 6E.1 antibody SCA-1 antibody Stem cell antigen 1
- Purification:
- Immunogen affinity purified
- Background:
- Sca-1, an 18 kDa phosphatidylinositol-anchored protein, is a member of the Ly-6 antigen family. Sca-1 is the most recognized HSC marker in mice with both Ly-6 haplotypes as it is expressed on multipotent HSCs. Sca-1+ HSCs can be found in the adult bone marrow, fetal liver and mobilized peripheral blood and spleen within the adult animal. An anti-Sca-1 Ab is frequently used in combination with negative selection for expression of a number of cell surface markers characteristic of differentiated cells of hematolymphoid lineages (Lin-) to identify and isolate murine HSCs.
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