Product Datasheet  
PKC alpha (Phospho-T638) Antibody  
Catalog Number: 13428  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P17252
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic phospho-peptide corresponding to residues surrounding Thr638 of human PKC alpha.
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:1,000-5,000
    IHC: 1:50-1:500
    ICC: 1:50-1:500

  • other_names：  
  • AAG6 antibody
    Aging associated gene 6 antibody
    aPKC antibody
    KPCA_HUMAN antibody
    PKC alpha antibody
    PKC-A antibody
    PKC-alpha antibody
    PKCA antibody
    PRKACA antibody
    PRKCA antibody
    Protei
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, ICC/IF, IHC, IP
  • Background：  
  • Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor-promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into many different isoforms (α, βI, βII, γ, δ, ε, ζ, η, θ, λ/ι, μ and ν). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC δ and ε are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.



 
© Signalway Biotechnology All Rights Reserved.