Product Datasheet
JunD(Phospho-S255) Antibody
Catalog Number: 13422
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P17535
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Synthetic phospho-peptide corresponding to residues surrounding Ser255 of human JunD.
- appl_detail:
- WB: 1:1,000
IHC: 1:50-1:200
ICC: 1:50-1:200
- other_names:
- Activator protein 1 antibody
AP 1 antibody
AP1 antibody
Jun D antibody
jun D proto oncogene antibody
Jund antibody
JunD FL isoform antibody
JUND_HUMAN antibody
Transcription factor jun D antibody
- Purification:
- ProA affinity purified
- Applications:
- WB, ICC/IF, IHC
- Background:
- The activator protein-1 (AP-1) transcription factor consists of either Jun/Jun homodimers or Fos/Jun heterodimeric complexes. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Jun B and Jun D have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family. Studies suggest that the two forms of Jun D may be due to internal initiation of translation.
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