Product Datasheet  
PKC zeta(Phospho-T560) Antibody  
Catalog Number: 13403  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q05513
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic phospho-peptide corresponding to residues surrounding Thr560 of human PKC zeta.
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:1,000-5,000
    IHC: 1:50-1:200


  • other_names:  
  • 14-3-3-zetaisoform antibody
    AI098070 antibody
    aPKCzeta antibody
    C80388 antibody
    EC 2.7.11.13 antibody
    KPCZ_HUMAN antibody
    nPKC zeta antibody
    nPKC-zeta antibody
    OTTHUMP00000001368 antibody
    OTTH
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, IHC
  • Background:  
  • Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into many different isoforms (α, βI, βII, γ, δ, ε, , h, θ, λ/ι, ? and n). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC δ and ε are independent of Ca++. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.



 
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