Product Datasheet
Cdk2(Phospho-Y15) Antibody
Catalog Number: 13399
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P24941
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Synthetic phospho-peptide corresponding to residues surrounding Tyr15 of human Cdk2.
- appl_detail:
- WB: 1:1,000
IHC: 1:50-1:200
- other_names:
- Cdc2 related protein kinase antibody
cdc2-related protein kinase antibody
CDC28 antibody
CDC2A antibody
Cdk 2 antibody
CDK1 antibody
CDK2 antibody
CDK2_HUMAN antibody
CDKN2 antibody
Cell devis
- Purification:
- ProA affinity purified
- Applications:
- WB, IHC, IP
- Background:
- In vertebrates, as in yeast, multiple cyclins have been identified, including a total of eight such regulatory proteins in mammals. In contrast to the situation in yeast, the Cdc2 p34 kinase is not the only catalytic subunit identified in vertebrates that can interact with cyclins. While Cdc2 p34 is essential for the G2 to M transition in vertebrate cells, a second Cdc2-related kinase has also been implicated in cell cycle control. This protein, designated cyclin-dependent kinase 2 (Cdk2) p33, also binds to cyclins and its kinase activity is temporally regulated during the cell cycle. Several additional Cdc2 p34-related cyclin dependent kinases have been identified. These include Cdk3-Cdk8, PCTAIRE-1-3 and KKIALRE.
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