Product Datasheet  
Hormone sensitive lipase (Phospho-S853) Antibody  
Catalog Number: 13391  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q05469
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic phospho-peptide corresponding to residues surrounding Ser853 of human Hormone sensitive lipase.
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:1,000-5,000



  • other_names:  
  • Hormone sensitive lipase antibody
    Hormone sensitive lipase testicular isoform antibody
    Hormone-sensitive lipase antibody
    HSL antibody
    LHS antibody
    Lipase hormone sensitive antibody
    LIPE antibody
    LIPS_HUMAN
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB
  • Background:  
  • HSL (hormone-sensitive lipase), a cytosolic neutral lipase regulated by reversible phosphorylation, catalyzes the rate limiting step in triglyceride lipolysis. HSL hydrolyzes stored triglycerides to free fatty acids in adipose and heart tissues. In organs with steroidogenic tissues, such as small intestine, HSL converts cholesteryl esters to free cholesterol for steroid hormone production. HSL is highly expressed in jejunal enterocytes and in the mucosa of the small intestine. Two major isoforms of HSL have been described resulting from the use of alternative translational start codons. The short isoform is expressed in adipose tissue while the long isoform is expressed in steroidogenic tissues such as testis. The long isoform, often referred to as testicular HSL contains an N-terminus of approximately 300 amino acids not present in the short isoform of HSL.



 
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