Product Datasheet  
SMC1(Phospho-S957) Antibody  
Catalog Number: 13387  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q14683
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic phospho-peptide corresponding to residues surrounding Ser957 of human SMC1.
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:1,000-5,000
    IHC:1:50-1:200
    ICC: 1:50-1:200

  • other_names：  
  • CDLS2 antibody
    DKFZp686L19178 antibody
    DXhXs423e antibody
    DXS423E antibody
    KIAA0178 antibody
    MGC138332 antibody
    OTTHUMP00000061876 antibody
    RP6 29D12.1 antibody
    SB1.8 antibody
    Segregation of m
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, IHC, ICC
  • Background：  
  • The SMC (structural maintenance of chromosomes) family of proteins form heterodimeric complexes that modulate sister chromatid cohesion and chromosome condensation for mitosis. The two distinct classes of SMC protein complexes are comprised of SMC1 (also designated SB1.8) with SMC3 (also designated HCAP for human chromosome-associated protein and Bamacan for the secreted proteoglycan), and SMC2 (also designated hCAP-E) with SMC4 (also designated hCAP-C). The SMC1/SMC3 complex is required for metaphase progression in mitotic cells and functions independently of the SMC2/SMC4 complex during the cell cycle. SMC1 is ubiqitiously expressed in various human tissues, including thymus, testis and colon. SMC3 is expressed as a nuclear protein in the colon, but can also occur as a secreted proteoglycan expressed in testis and brain. The secreted proteoglycan contains several glycosylation sites and is thought to play a role in basement membrane physiology.



 
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