Product Datasheet  
IKB alpha(Phospho-S32) Antibody  
Catalog Number: 13376  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P25963
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic phospho-peptide corresponding to residues surrounding Ser32 of human IKB alpha.
  • reactivity:  
  • Hu
  • appl_detail:  
  • WB: 1:1,000

    ICC: 1:50-1:200

  • other_names:  
  • I kappa B alpha antibody
    I-kappa-B-alpha antibody
    IkappaBalpha antibody
    IkB-alpha antibody
    IKBA antibody
    IKBA_HUMAN antibody
    IKBalpha antibody
    MAD 3 antibody
    MAD3 antibody
    Major histocompatibi
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC, IP
  • Background:  
  • On the basis of both functional and structural considerations, members of the IκB family of proteins can be divided into four groups. The first of these groups, IκB-α, includes the avian protein pp40 and the mammalian MAD-3, both of which inhibit binding of p50-p65 NFkB complex or Rel protein to their cognate binding sites but do not inhibit the binding of p50 homodimer to κB sites, suggesting that the IκB-α family binds to the p65 subunit of p50-p65 heterocomplex through ankyrin repeats. The second member of the IκB family is represented by a protein designated IκB-β. The third group of IκB proteins is represented by IκB-γ, which is identical in sequence with the C-terminal domain of the p110 precursor of NFkB p50 and is expressed predominantly in lymphoid cells. An additional IκB family member, IκB-ε, has several phosphorylated forms and is primarily found complexed with Rel A and/or c-Rel.



 
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