Product Datasheet  
MEK1(Phospho-S218/S222) Antibody  
Catalog Number: 13373  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q02750
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic phospho-peptide corresponding to residues surrounding Ser218 and 222 of human MEK1.
  • reactivity:  
  • Hu
  • appl_detail:  
  • WB: 1:1,000-1:2,000
    IHC: 1:50-1:200
    ICC: 1:50-1:200

  • other_names:  
  • Dual specificity mitogen activated protein kinase kinase 1 antibody
    Dual specificity mitogen-activated protein kinase kinase 1 antibody
    ERK activator kinase 1 antibody
    MAP kinase kinase 1 antibody
    MAP kinase/Erk kinase 1 antibo
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC/IF, IHC, IP
  • Background:  
  • Activation of extracellular signal-regulated kinase (ERK) or mitogen-activated protein kinase by MEK (mitogen-activated protein kinase or extracellular signal-regulated kinase kinase) is an essential event in the mitogenic growth factor-induced signal transduction pathway. Phosphorylation of MEKs correlates with their ability to phosphorylate and activate ERKs. MEK1 and MEK2 can also be activated by autophosphorylation. Lipopolysaccharide activates many of the MAPK family members of the immediate upstream MAPK activator MEK1, MEK2, and MEK3. In plants, MEK can phosphorylate and activate MAPK, and that Tyr phosphorylation is critical for the catalytic activity of MAPK in plants.



 
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