Product Datasheet  
eIF4E (Phospho-S209) Antibody  
Catalog Number: 13364  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P06730
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic phospho-peptide corresponding to residues surrounding Ser209 of human eIF4E.
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:1,000-5,000
    IHC: 1:50-1:200
    ICC: 1:50-1:200

  • other_names:  
  • AUTS19 antibody
    CBP antibody
    eIF 4E antibody
    eIF 4F 25 kDa subunit antibody
    EIF 4F antibody
    eIF-4E antibody
    eIF-4F 25 kDa subunit antibody
    eIF4E antibody
    EIF4E1 antibody
    EIF4EL1 antibody
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC, IHC, IP
  • Background:  
  • The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF4F exists in vitro as a trimeric complex of eIF4E, eIF4A and eIF4G. Together, the complex allows ribosome binding to mRNA by inducing the unwinding of mRNA secondary structures. eIF4E binds to the mRNA "cap" during an early step in the initiation of protein synthesis. eIF4A acts as an ATP-dependent RNA helicase. eIF4G acts as a bridge between eIF4E, eIF4A and the eIF3 complex.



 
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