Product Datasheet
ESRRB Antibody
Catalog Number: 48164
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O95718
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- appl_detail:
- WB: 1:500-1:1000
IHC: 1:200
ICC: 1:100-1:200
- other_names:
- Err 2 antibody ERR b antibody ERR B2 antibody ERR beta 2 antibody ERR beta antibody ERR beta-2 antibody ERR-beta antibody Err2 antibody ERR2_HUMAN antibody ERRB 2 antibody ERRb antibody ERRB2 antibody
- Purification:
- Immunogen affinity purified
- Applications:
- WB, ICC, IHC
- Background:
- Steroid hormone receptors are found on the plasma membrane, in the cytosol and also in the nucleus of target cells. They are generally intracellular receptors and initiate signal transduction for steroid hormones which lead to changes in gene expression over a time period of hours to days. Defects in ESRRB are the cause of deafness autosomal recessive type 35 (DFNB35). DFNB35 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
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