Product Datasheet  
NF-kB p65 (Phospho-S529) Antibody  
Catalog Number: 13347  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q04206
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide conjugated to Keyhole Limpet Haemocyanin (KLH)
  • reactivity:  
  • Hu
  • appl_detail:  
  • WB: 1:500-1:1,000



    FC: 1:50-1:100
  • other_names:  
  • Avian reticuloendotheliosis viral (v rel) oncogene homolog A antibody
    MGC131774 antibody
    NF kappa B p65delta3 antibody
    NFKB3 antibody
    Nuclear Factor NF Kappa B p65 Subunit antibody
    Nuclear factor NF-kappa-B p65 subunit a
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, IP, FC
  • Background:  
  • Proteins encoded by the v-Rel viral oncogene and its cellular homolog, c-Rel, are members of a family of transcription factors that include the two subunits of the transcription factor NκB (p50 and p65) and the Drosophila maternal morphogen, dorsal. Both proteins specifically bind to DNA sequences that are the same or slight variations of the 10 bp κB sequence in the immunoglobulin κ light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NFκB is activated and NFκB is subsequently transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors for two distinct proteins of the same size have been described, designated p105 and p100. The p105 precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule, designated pdI, binds to p50 and regulates its activity.



 
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