Product Datasheet  
RNF217 Antibody  
Catalog Number: 47802  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q8TC41
    NCBI Gene ID:154214
    Gene Accssion:NP_001273327
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide of human RNF217
  • reactivity：  
  • Hu, Ms
  • appl_detail：  
  • IHC dilution:1: 20-100
  • other_names：  
  • OSTL; IBRDC1; C6orf172; dJ84N20.1
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total RNF217 protein.
  • Applications：  
  • IHC
  • Background：  
  • This protein encoded by this gene is a member of the RING1-IBR-RING24 (RBR) ubiquitin protein ligase family, and it belongs to a subfamily of these proteins that contain a transmembrane domain. This protein can interact with the HAX1 anti-apoptotic protein via its C-terminal RING finger motif, which suggests a role in apoptosis signaling. It is thought that deregulation of this gene can be a mechanism in leukemogenesis. Mutations in the region encoding the protein GXXXG motif, which appears to be necessary for protein self-association, have been found in human cancers. Alternative splicing of this gene results in multiple transcript variants.?



 
© Signalway Biotechnology All Rights Reserved.