Product Datasheet
HOXD4 Antibody
Catalog Number: 47800
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P09016
NCBI Gene ID:3233
Gene Accssion:NP_055436
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human HOXD4
- appl_detail:
- IHC dilution:1: 10-50
- other_names:
- HOX4; HOX4B; HHO.C13; HOX-5.1; Hox-4.2
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total HOXD4 protein.
- Background:
- This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.
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