Product Datasheet
H1FOO Antibody
Catalog Number: 47794
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8IZA3
NCBI Gene ID:132243
Gene Accssion:NP_722575
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human H1FOO
- appl_detail:
- IHC dilution:1: 30-150
- other_names:
- H1.8; H1oo; osH1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total H1FOO protein.
- Background:
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a replication-independent histone that is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The related mouse gene is expressed only in oocytes.
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