Product Datasheet
PTGDR2 Antibody
Catalog Number: 47774
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9Y5Y4
NCBI Gene ID:11251
Gene Accssion:NP_004769
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human PTGDR2
- appl_detail:
- WB dilution:1:200-1000
IHC dilution:1: 20-100
- other_names:
- DP2; DL1R; CD294; CRTH2; GPR44
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total PTGDR2 protein.
- Background:
- This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.
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