Product Datasheet
FECH Antibody
Catalog Number: 47761
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P22830
NCBI Gene ID:2235
Gene Accssion:NP_000131
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human FECH
- appl_detail:
- WB dilution:1:500-2000
IHC dilution:1: 50-300
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total FECH protein.
- Background:
- The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.
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