Product Datasheet
ORC4 Antibody
Catalog Number: 47721
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O43929
NCBI Gene ID:5000
Gene Accssion:BC005388
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human ORC4
- appl_detail:
- WB dilution:1:500-2000
IHC dilution:1: 50-300
- other_names:
- ORC4L; ORC4P
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total ORC4 protein.
- Background:
- The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.
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