Product Datasheet
HENMT1 Antibody
Catalog Number: 47706
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q5T8I9
NCBI Gene ID:113802
Gene Accssion:BC012198
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human HENMT1
- appl_detail:
- WB dilution:1:500-2000
IHC dilution:1: 30-150
- other_names:
- HEN1; C1orf59
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total HENMT1 protein.
- Background:
- Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.
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