Product Datasheet
HSPB11 Antibody
Catalog Number: 47700
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9Y547
NCBI Gene ID:51668
Gene Accssion:NP_057210
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human HSPB11
- appl_detail:
- IHC dilution:1: 20-100
- other_names:
- PP25; IFT25; C1orf41; HSPCO34
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total HSPB11 protein.
- Background:
- Component of the IFT complex B required for sonic hedgehog/SHH signaling. May mediate transport of SHH components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport of SHH signaling molecules within the cilium. Not required for ciliary assembly (By similarity).
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