Product Datasheet
KDM2B Antibody
Catalog Number: 47690
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8NHM5
NCBI Gene ID:84678
Gene Accssion:NP_115979
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human KDM2B
- appl_detail:
- IHC dilution:1: 50-200
- other_names:
- CXXC2; Fbl10; PCCX2; FBXL10; JHDM1B
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total KDM2B protein.
- Background:
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
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