Product Datasheet
PEMT Antibody
Catalog Number: 47675
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9UBM1
NCBI Gene ID:10400
Gene Accssion:NP_009100
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human PEMT
- appl_detail:
- WB dilution:1:1000-5000
IHC dilution:1: 50-300
- other_names:
- PLMT; PNMT; PEAMT; PEMPT; PEMT2
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total PEMT protein.
- Background:
- Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
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