Product Datasheet
IRX5 Antibody
Catalog Number: 47665
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P78411
NCBI Gene ID:10265
Gene Accssion:NP_005844
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human IRX5
- appl_detail:
- WB dilution:1:200-1000
IHC dilution:1: 30-150
- other_names:
- HMMS; IRXB2; IRX-2a
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total IRX5 protein.
- Background:
- This gene encodes a member of the iroquois homeobox gene family, which are involved in several embryonic developmental processes. Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation, and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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