Product Datasheet
SETD1A Antibody
Catalog Number: 47638
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O15047
NCBI Gene ID:9739
Gene Accssion:NP_055527
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human SETD1A
- appl_detail:
- IHC dilution:1: 30-150
- other_names:
- Set1; KMT2F; Set1A
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total SETD1A protein.
- Background:
- The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily.
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