Product Datasheet
HPR Antibody
Catalog Number: 47637
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P00739
NCBI Gene ID:3250
Gene Accssion:NP_066275
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human HPR
- appl_detail:
- WB dilution:1:200-1000
IHC dilution:1: 40-200
- other_names:
- HP; A-259H10.2
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total HPR protein.
- Background:
- This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer.
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