Product Datasheet
TLX1 Antibody
Catalog Number: 47635
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P31314
NCBI Gene ID:3195
Gene Accssion:NP_005512
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human TLX1
- appl_detail:
- IHC dilution:1: 10-50
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total TLX1 protein.
- Background:
- This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants.
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