Product Datasheet
HLA-DQA2 Antibody
Catalog Number: 47631
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P01906
NCBI Gene ID:3118
Gene Accssion:NP_064440
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human HLA-DQA2
- appl_detail:
- IHC dilution:1: 20-100
- other_names:
- HLA-DXA; HLADQA2; DX-ALPHA
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total HLA-DQA2 protein.
- Background:
- This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells.
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