Product Datasheet
GPR153 Antibody
Catalog Number: 47606
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q6NV75
NCBI Gene ID:387509
Gene Accssion:NP_997253
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human GPR153
- appl_detail:
- IHC dilution:1: 30-150
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total GPR153 protein.
- Background:
- This gene encodes an integral membrane protein that belongs to the Class A rhodopsin superfamily of G protein coupled receptors. The encoded protein is expressed primarily in the central nervous system. A knockdown of the orthologous gene in rat is associated with a significant reduction in food intake and impaired decision making ability. Mutations in this gene are associated with schizophrenia, autism, and other neuropsychiatric disorders. The expression of this gene is activated by the glioma-associated oncogene homolog 1 transcription factor which, in turn, is activated by sonic hedgehog in normal and tumorigenic cells.
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