Product Datasheet
ADGRG1 Antibody
Catalog Number: 47600
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9Y653
NCBI Gene ID:9289
Gene Accssion:NP_005673
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human ADGRG1
- appl_detail:
- IHC dilution:1: 20-100
- other_names:
- BFPP; BPPR; GPR56; TM7LN4; TM7XN1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total ADGRG1 protein.
- Background:
- This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants.
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