Product Datasheet
GEMIN4 Antibody
Catalog Number: 47573
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P57678
NCBI Gene ID:50628
Gene Accssion:NP_056536
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human GEMIN4
- appl_detail:
- IHC dilution:1: 30-150
- other_names:
- p97; HC56; HCAP1; HHRF-1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total GEMIN4 protein.
- Background:
- The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
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