Product Datasheet
CTDP1 Antibody
Catalog Number: 47550
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9Y5B0
NCBI Gene ID:9150
Gene Accssion:NP_004706
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human CTDP1
- appl_detail:
- WB dilution:1:500-2000
IHC dilution:1: 50-300
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CTDP1 protein.
- Background:
- This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.?
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