Product Datasheet
PIEZO2 Antibody
Catalog Number: 47543
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9H5I5
NCBI Gene ID:63895
Gene Accssion:NP_071351
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human PIEZO2
- appl_detail:
- IHC dilution:1: 50-300
- other_names:
- DA3; DA5; MWKS; DAIPT; FAM38B; HsT748; HsT771; FAM38B2; C18orf30; C18orf58
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total PIEZO2 protein.
- Background:
- The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.?
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