Product Datasheet
ERAP2 Antibody
Catalog Number: 47522
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q6P179
NCBI Gene ID:64167
Gene Accssion:NP_071745
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human ERAP2
- appl_detail:
- IHC dilution:1: 10-50
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total ERAP2 protein.
- Background:
- This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5.?
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