Product Datasheet
ZGPAT Antibody
Catalog Number: 47485
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8N5A5
NCBI Gene ID:84619
Gene Accssion:NP_115916
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human ZGPAT ?
- appl_detail:
- IHC dilution:1: 50-200
- other_names:
- ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847; RP4-583P15.3
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total ZGPAT ? protein.
- Background:
- ZGPAT (Zinc finger CCCH-type with G patch domain-containing protein), also known as zinc finger CCCH domain-containing protein 9 (ZC3HDC9) and G patch domain-containing protein 6 (GPATC6), is a 531 amino acid protein that contains a G-patch domain, which is typically found within RNA-binding proteins. Proteins that contain the G-patch domain include some tumor suppressor and DNA-damage repair proteins. ZGPAT also contains one C3H1-type zinc finger, which further supports its probable role as an RNA-binding protein. The gene encoding ZGPAT is inactivated via differential methylation in a oligodendroglioma cell line, suggesting that ZGPAT may have utility as a biomarker. There are two isoforms of ZGPAT that are produced as a result of alternative splicing events.
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