Product Datasheet
ZAK Antibody
Catalog Number: 47475
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9NYL2
NCBI Gene ID:51776
Gene Accssion:NP_057737
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human ZAK ?
- appl_detail:
- IHC dilution:1: 50-200
- other_names:
- pk; AZK; MLT; MRK; MLK7; MLTK; mlklak
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total ZAK ? protein.
- Background:
- This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells.?
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