Product Datasheet
XPNPEP3 Antibody
Catalog Number: 47467
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9NQH7
NCBI Gene ID:63929
Gene Accssion:NP_071381
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human XPNPEP3 ?
- appl_detail:
- WB dilution:1:200-1000
IHC dilution:1: 25-100
- other_names:
- APP3; NPHPL1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total XPNPEP3 ? protein.
- Background:
- The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.
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