Product Datasheet
NMU Antibody
Catalog Number: 47449
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P48645
NCBI Gene ID:10874
Gene Accssion:BC012908
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human NMU
- appl_detail:
- IHC dilution:1: 50-200
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total NMU protein.
- Background:
- This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide.
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