Product Datasheet
PAM16 Antibody
Catalog Number: 47431
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9Y3D7
NCBI Gene ID:51025
Gene Accssion:BC005024
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human PAM16
- appl_detail:
- IHC dilution:1: 50-200
- other_names:
- TIM16; MAGMAS; SMDMDM; TIMM16; CGI-136
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total PAM16 protein.
- Background:
- This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia, an early lethal skeletal dysplasia characterized by short stature, developmental delay and other skeletal abnormalities.?
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