Product Datasheet  
PAM16 Antibody  
Catalog Number: 47431  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q9Y3D7
    NCBI Gene ID:51025
    Gene Accssion:BC005024
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein of human PAM16
  • reactivity:  
  • Hu, Ms
  • appl_detail:  
  • IHC dilution:1: 50-200
  • other_names:  
  • TIM16; MAGMAS; SMDMDM; TIMM16; CGI-136
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total PAM16 protein.
  • Applications:  
  • IHC
  • Background:  
  • This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia, an early lethal skeletal dysplasia characterized by short stature, developmental delay and other skeletal abnormalities.?



 
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