Product Datasheet
PAPSS2 Antibody
Catalog Number: 47420
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O95340
NCBI Gene ID:9060
Gene Accssion:BC009894
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human PAPSS2
- appl_detail:
- WB dilution:1:1000-5000
IHC dilution:1: 80-400
- other_names:
- SK2; BCYM4; ATPSK2
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total PAPSS2 protein.
- Background:
- Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.
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