Product Datasheet
ZFYVE27 Antibody
Catalog Number: 47389
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q5T4F4
NCBI Gene ID:118813
Gene Accssion:BC030621
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human ZFYVE27
- appl_detail:
- WB dilution:1:500-2000
IHC dilution:1: 50-300
- other_names:
- SPG33; PROTRUDIN
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total ZFYVE27 protein.
- Background:
- This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.
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