Product Datasheet
MEST Antibody
Catalog Number: 47387
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q5EB52
NCBI Gene ID:4232
Gene Accssion:BC002413
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human MEST
- appl_detail:
- WB dilution:1:500-2000
IHC dilution:1: 50-300
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total MEST protein.
- Background:
- This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15.
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