Product Datasheet
BEX2 Antibody
Catalog Number: 47332
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9BXY8
NCBI Gene ID:84707
Gene Accssion:BC015522
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human BEX2
- appl_detail:
- IHC dilution:1: 50-300
- other_names:
- BEX1; DJ79P11.1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total BEX2 protein.
- Background:
- This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene.
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