Product Datasheet
PPM1G Antibody
Catalog Number: 47308
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O15355
NCBI Gene ID:5496
Gene Accssion:BC000057
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human PPM1G
- appl_detail:
- IHC dilution:1: 40-200
- other_names:
- PP2CG; PPP2CG; PP2CGAMMA
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total PPM1G protein.
- Background:
- The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
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