Product Datasheet
DCD Antibody
Catalog Number: 47246
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P81605
NCBI Gene ID:117159
Gene Accssion:BC062682
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human DCD
- appl_detail:
- IHC dilution:1: 30-150
- other_names:
- PIF; AIDD; DSEP; HCAP; DCD-1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total DCD protein.
- Background:
- This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms.
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