Product Datasheet
YAP1 Antibody
Catalog Number: 47241
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P46937
NCBI Gene ID:10413
Gene Accssion:NP_001123617
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human YAP1
- appl_detail:
Immunofluorescence:1: 20-100
- other_names:
- YAP; YKI; COB1; YAP2; YAP65
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total YAP1 protein.
- Background:
- This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
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