Product Datasheet
SGCD Antibody
Catalog Number: 47201
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q92629
NCBI Gene ID:6444
Gene Accssion:BC020740
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human SGCD
- appl_detail:
- Western blotting:1:200-1000
Immunofluorescence:1: 25-100
- other_names:
- SGD; DAGD; 35DAG; CMD1L; SGCDP; SG-delta
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total SGCD protein.
- Background:
- The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.?
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