Product Datasheet
SGCA Antibody
Catalog Number: 47200
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q16586
NCBI Gene ID:6442
Gene Accssion:BC025702
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human SGCA
- appl_detail:
Immunofluorescence:1: 20-100
- other_names:
- ADL; DAG2; 50DAG; DMDA2; LGMD2D; SCARMD1; adhalin
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total SGCA protein.
- Background:
- This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
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