Product Datasheet
SF3A3 Antibody
Catalog Number: 47199
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q12874
NCBI Gene ID:10946
Gene Accssion:BC002395
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human SF3A3
- appl_detail:
Immunofluorescence:1: 20-100
- other_names:
- PRP9; PRPF9; SAP61; SF3a60
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total SF3A3 protein.
- Background:
- This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.
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