Product Datasheet
RNF19A Antibody
Catalog Number: 47193
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9NV58
NCBI Gene ID:25897
Gene Accssion:NP_056250
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human RNF19A
- appl_detail:
Immunofluorescence:1: 25-100
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total RNF19A protein.
- Background:
- This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants.
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